Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASSF6Ras association domain-containing protein 6 isoform X1. (413 aa)    
Predicted Functional Partners:
STK3
Serine/threonine-protein kinase 3 isoform X1.
    
 0.966
STK4
Serine/threonine-protein kinase 4.
    
 0.926
MDM2
E3 ubiquitin-protein ligase Mdm2 isoform X1.
    
 0.704
KDM3A
[histone H3]-dimethyl-L-lysine9 demethylase.
    
   0.603
APBB2
Amyloid beta A4 precursor protein-binding family B member 2 isoform X1.
      
 0.539
RASSF10
Ras association domain-containing protein 9/10.
   
  
 0.512
MTUS1
Microtubule-associated tumor suppressor 1 isoform X1.
    
 0.500
RASSF7
Ras association domain-containing protein 7 isoform X1.
   
  
 0.497
USP10
Ubiquitin carboxyl-terminal hydrolase 10 isoform X1.
      
 0.493
INSYN2B
Protein FAM196B isoform X1.
      
 0.490
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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