Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHBDD1Rhomboid-related protein 4 isoform X1. (316 aa)    
Predicted Functional Partners:
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
    
 
 0.839
KLHL31
Kelch-like protein 31.
      
 0.711
TMEM70
Transmembrane protein 70, mitochondrial.
      
 0.695
TMEM214
Transmembrane protein 214 isoform X1.
      
 0.690
TMEM38A
Trimeric intracellular cation channel type A.
      
 0.656
POPDC2
Popeye domain-containing protein 2 isoform X1.
    
 
 0.652
SAE1
SUMO-activating enzyme subunit 1 isoform X1.
      
 0.593
FAM118A
Protein FAM118A isoform X1.
    
 0.543
SPATA5
Spermatogenesis-associated protein 5 isoform X1.
    
 
 0.531
SPATA5L1
Spermatogenesis-associated protein 5-like protein 1 isoform X1.
    
 
 0.531
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.