STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.968
RAC2
Rac family small GTPase 2.
   
 0.955
RAC1
Ras-related C3 botulinum toxin substrate 1 isoform X1.
   
 0.944
ENSPPRP00000015553
annotation not available
   
 0.929
ENSPPRP00000025718
annotation not available
   
 0.929
CDC42
Cell division control protein 42 homolog.
   
 0.929
MAPK1
Mitogen-activated protein kinase 1/3.
    
 0.912
CD44
CD44 molecule (Indian blood group).
   
 0.909
MAPK3
Mitogen-activated protein kinase 1/3.
    
 0.908
IQGAP2
Ras GTPase-activating-like protein IQGAP2 isoform X1.
     
  0.894
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.