Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MOKMAPK/MAK/MRK overlapping kinase isoform X1. (419 aa)    
Predicted Functional Partners:
MYRF
Myelin regulatory factor.
    
 0.656
MYRFL
Myelin regulatory factor-like protein isoform X1.
    
 0.656
CDC6
Cell division control protein 6 homolog.
    
 
 0.608
MCM2
DNA replication licensing factor MCM2.
    
 
 0.602
MCM3
DNA replication licensing factor MCM3.
    
   0.598
MCM5
DNA replication licensing factor MCM5.
    
   0.598
MCM6
DNA replication licensing factor MCM6.
    
   0.598
ORC3
Origin recognition complex subunit 3 isoform X1.
    
   0.598
MCM7
DNA replication licensing factor MCM7 isoform X1.
    
   0.598
CDT1
Chromatin licensing and DNA replication factor 1.
    
   0.598
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]