Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HDAC5Histone deacetylase 5 isoform X1. (1122 aa)    
Predicted Functional Partners:
CAMK4
Calcium/calmodulin-dependent protein kinase type IV isoform X1.
   
 0.920
HDAC4
Histone deacetylase 4/5.
     
  0.894
MACROH2A1
Core histone macro-H2A.1 isoform X1.
    
 0.859
MACROH2A2
Core histone macro-H2A.2.
    
 0.858
H2BU1
Histone H2B type 3-B.
    
 0.850
H2AX
Histone H2AX.
    
 0.848
LOC109275092
Histone H2B subacrosomal variant-like.
    
 0.833
MEF2D
Myocyte-specific enhancer factor 2D isoform X1.
   
 
 0.809
ENSPPRP00000012550
Histone H2B type 1-A-like.
    
 0.791
H2BC1
Histone H2B type 1-A.
    
 0.791
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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