Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MBD3Methyl-CpG-binding domain protein 3 isoform X1. (291 aa)    
Predicted Functional Partners:
MTA2
Metastasis-associated protein MTA2 isoform X1.
   
 0.948
MTA1
Metastasis-associated protein MTA1.
   
 0.907
MTA3
Metastasis-associated protein MTA3 isoform X1.
   
 0.893
GATAD2A
Transcriptional repressor p66-alpha isoform X1.
   
 0.892
CHD4
Chromodomain-helicase-DNA-binding protein 4 isoform X1.
    
 0.891
GATAD2B
Transcriptional repressor p66-beta isoform X1.
   
 0.891
CHD3
Chromodomain-helicase-DNA-binding protein 3.
    
 0.861
RBBP4
Histone-binding protein RBBP4.
   
 0.840
CHD5
Chromodomain-helicase-DNA-binding protein 5.
    
 0.812
RBBP7
Histone-binding protein RBBP7 isoform X1.
   
 0.805
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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