Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACANAggrecan core protein isoform X1. (720 aa)    
Predicted Functional Partners:
HAPLN1
Hyaluronan and proteoglycan link protein 1 isoform X1.
   
 0.955
TNC
Tenascin isoform X1.
   
 0.905
ADAMTS4
A disintegrin and metalloproteinase with thrombospondin motifs 4.
    
 0.905
ADAMTS5
A disintegrin and metalloproteinase with thrombospondin motifs 5.
    
 0.904
TNR
Tenascin-R.
   
 0.903
COL2A1
Collagen alpha-1(II) chain isoform X1.
   
 0.850
FMOD
Fibromodulin.
    
 0.789
MMP13
Matrix metalloproteinase-13 (collagenase 3).
   
 0.784
SOX9
Transcription factor SOX9 (SOX group E).
      
 0.775
LUM
Lumican.
   
 0.761
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.