STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACANAggrecan core protein isoform X1. (720 aa)    
Predicted Functional Partners:
HAPLN1
Hyaluronan and proteoglycan link protein 1 isoform X1.
   
0.960
TNR
Tenascin-R.
   
 0.940
COL2A1
Collagen alpha-1(II) chain isoform X1.
   
 0.880
COMP
Cartilage oligomeric matrix protein.
   
 0.866
FMOD
Fibromodulin.
    
 0.862
TNC
Tenascin isoform X1.
   
 0.850
BGN
Biglycan.
   
 0.843
SOX9
Transcription factor SOX9 (SOX group E).
      
 0.840
ADAMTS4
A disintegrin and metalloproteinase with thrombospondin motifs 4.
    
 0.815
ADAMTS5
A disintegrin and metalloproteinase with thrombospondin motifs 5.
     
 0.806
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.