DENND4C protein (Panthera pardus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DENND4C

DENN domain-containing protein 4C isoform X1. (1957 aa)

Predicted Functional Partners:

MINDY1

0.749

WHAMM

0.735

ANKFY1

0.708

RAB10

0.665

DENND1A

0.631

AVL9

0.629

RIC1

0.608

VMP1

0.608

DENND5A

0.595

DENND5B

0.590

Your Current Organism:

Panthera pardus

NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKFY1	DENND4C	ENSPPRP00000000658	ENSPPRP00000001779	Ankyrin repeat and FYVE domain containing 1.	DENN domain-containing protein 4C isoform X1.	0.708
ANKFY1	MINDY1	ENSPPRP00000000658	ENSPPRP00000007940	Ankyrin repeat and FYVE domain containing 1.	Ubiquitin carboxyl-terminal hydrolase MINDY-1/2.	0.741
ANKFY1	VMP1	ENSPPRP00000000658	ENSPPRP00000015550	Ankyrin repeat and FYVE domain containing 1.	Vacuole membrane protein 1 isoform X1.	0.434
ANKFY1	WHAMM	ENSPPRP00000000658	ENSPPRP00000022472	Ankyrin repeat and FYVE domain containing 1.	WASP homolog associated with actin, golgi membranes and microtubules.	0.648
AVL9	DENND1A	ENSPPRP00000006375	ENSPPRP00000000993	Late secretory pathway protein AVL9 homolog.	DENN domain containing 1A.	0.512
AVL9	DENND4C	ENSPPRP00000006375	ENSPPRP00000001779	Late secretory pathway protein AVL9 homolog.	DENN domain-containing protein 4C isoform X1.	0.629
AVL9	DENND5A	ENSPPRP00000006375	ENSPPRP00000028808	Late secretory pathway protein AVL9 homolog.	DENN domain-containing protein 5A isoform X1.	0.504
AVL9	DENND5B	ENSPPRP00000006375	ENSPPRP00000016848	Late secretory pathway protein AVL9 homolog.	DENN domain containing 5B.	0.612
AVL9	RIC1	ENSPPRP00000006375	ENSPPRP00000003010	Late secretory pathway protein AVL9 homolog.	RAB6A-GEF complex partner protein 1 isoform X1.	0.894
DENND1A	AVL9	ENSPPRP00000000993	ENSPPRP00000006375	DENN domain containing 1A.	Late secretory pathway protein AVL9 homolog.	0.512
DENND1A	DENND4C	ENSPPRP00000000993	ENSPPRP00000001779	DENN domain containing 1A.	DENN domain-containing protein 4C isoform X1.	0.631
DENND1A	DENND5A	ENSPPRP00000000993	ENSPPRP00000028808	DENN domain containing 1A.	DENN domain-containing protein 5A isoform X1.	0.631
DENND1A	DENND5B	ENSPPRP00000000993	ENSPPRP00000016848	DENN domain containing 1A.	DENN domain containing 5B.	0.556
DENND1A	RIC1	ENSPPRP00000000993	ENSPPRP00000003010	DENN domain containing 1A.	RAB6A-GEF complex partner protein 1 isoform X1.	0.437
DENND4C	ANKFY1	ENSPPRP00000001779	ENSPPRP00000000658	DENN domain-containing protein 4C isoform X1.	Ankyrin repeat and FYVE domain containing 1.	0.708
DENND4C	AVL9	ENSPPRP00000001779	ENSPPRP00000006375	DENN domain-containing protein 4C isoform X1.	Late secretory pathway protein AVL9 homolog.	0.629
DENND4C	DENND1A	ENSPPRP00000001779	ENSPPRP00000000993	DENN domain-containing protein 4C isoform X1.	DENN domain containing 1A.	0.631
DENND4C	DENND5A	ENSPPRP00000001779	ENSPPRP00000028808	DENN domain-containing protein 4C isoform X1.	DENN domain-containing protein 5A isoform X1.	0.595
DENND4C	DENND5B	ENSPPRP00000001779	ENSPPRP00000016848	DENN domain-containing protein 4C isoform X1.	DENN domain containing 5B.	0.590
DENND4C	MINDY1	ENSPPRP00000001779	ENSPPRP00000007940	DENN domain-containing protein 4C isoform X1.	Ubiquitin carboxyl-terminal hydrolase MINDY-1/2.	0.749