Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2 isoform X1. (443 aa)    
Predicted Functional Partners:
FKBP10
Peptidyl-prolyl cis-trans isomerase FKBP10.
   
 0.804
MFAP5
Microfibrillar-associated protein 5 isoform X1.
   
 
 0.724
MFAP2
Microfibrillar-associated protein 2.
   
 0.718
MRGPRF
Mas-related G-protein coupled receptor member F isoform X1.
    
 0.703
MYO16
Unconventional myosin-XVI.
   
 0.703
ENSPPRP00000025332
annotation not available
   
 0.697
COL6A2
Collagen alpha-2(VI) chain isoform X1.
   
 0.648
ATP6V0A2
V-type proton ATPase 116 kDa subunit a isoform X1.
    
 0.647
COL16A1
Collagen alpha-1(XVI) chain isoform X1.
   
 0.633
VGLL3
Transcription cofactor vestigial-like protein 3 isoform X1.
   
  
 0.621
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (16%) [HD]