Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LTN1E3 ubiquitin-protein ligase listerin. (1808 aa)    
Predicted Functional Partners:
NEMF
Nuclear export mediator factor NEMF isoform X1.
   
 0.989
TCF25
Transcription factor 25 isoform X1.
   
 0.985
ERMN
Ermin.
   
 0.882
UBC
Polyubiquitin-C.
    
 0.846
RPL8
Large subunit ribosomal protein L8e.
    
  0.839
NPLOC4
Nuclear protein localization protein 4 homolog.
   
 0.816
RPL3
60S ribosomal protein L3 isoform X1.
    
 0.806
RPL3L
Large subunit ribosomal protein L3e.
    
 0.797
FAAP100
Fanconi anemia core complex-associated protein 100.
   
 0.787
ENSPPRP00000003468
annotation not available
    
 0.766
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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