Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDH2Cadherin 2, type 1, N-cadherin. (906 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.941
JUP
Junction plakoglobin.
   
 0.922
CTNND1
Catenin (cadherin-associated protein), delta 1.
    
 0.877
CTNNA2
Catenin alpha 2.
   
 0.834
CTNNA1
Catenin alpha-1.
   
 0.834
PTPN1
Tyrosine-protein phosphatase non-receptor type 1 isoform X1.
    
 0.751
CDH11
Cadherin 11, type 2, OB-cadherin.
  
0.743
CDH7
Cadherin-7 isoform X1.
   
0.734
CDH1
Cadherin 1, type 1, E-cadherin.
    
0.731
CDH8
Cadherin 8.
  
 
0.730
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.