Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COILCoilin isoform X1. (579 aa)    
Predicted Functional Partners:
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
     
 0.716
NME8
Thioredoxin domain-containing protein 3 isoform X1.
  
 0.591
TRAF7
E3 ubiquitin-protein ligase TRAF7.
   
 0.549
WDR90
WD repeat-containing protein 90-like.
    
  0.525
RIPK4
Receptor interacting serine/threonine kinase 4.
  
 0.490
TONSL
NF-kappa-B inhibitor-like protein 2.
   
 0.450
DBT
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
    
 0.436
BCKDHB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
    
 0.435
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1.
   
 0.433
CHEK2
Serine/threonine-protein kinase Chk2 isoform X1.
    
 
 0.429
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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