Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAF1RNA polymerase II-associated factor 1 homolog. (528 aa)    
Predicted Functional Partners:
CTR9
RNA polymerase-associated protein CTR9 homolog.
   
 0.998
CDC73
Parafibromin isoform X1.
   
 0.998
LEO1
RNA polymerase-associated protein LEO1 isoform X1.
   
 0.997
WDR61
WD repeat-containing protein 61 isoform X1.
   
 0.996
RTF1
RNA polymerase-associated protein RTF1 homolog.
   
 0.993
POLR2A
LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1.
    
 0.938
SUPT16H
FACT complex subunit SPT16.
    
 0.937
SSRP1
Structure-specific recognition protein 1.
   
 0.932
CINP
Cyclin-dependent kinase 2-interacting protein isoform X1.
   
 0.907
SUPT5H
Transcription elongation factor SPT5 isoform X1.
   
 0.898
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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