Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PNKD-2PNKD metallo-beta-lactamase domain containing. (142 aa)    
Predicted Functional Partners:
SUOX
Sulfite oxidase, mitochondrial isoform X1.
   
 
 0.869
PRRT2
Proline rich transmembrane protein 2.
    
 
 0.559
TMEM91
Transmembrane protein 91 isoform X1.
      
 0.529
PET100
Protein PET100 homolog, mitochondrial.
   
 
 0.504
TMEM25
Transmembrane protein 25 isoform X1.
      
 0.498
MCEE
Methylmalonyl-CoA epimerase, mitochondrial isoform X1.
  
 0.498
GLO1
Lactoylglutathione lyase.
  
 0.498
ASIC4
Acid-sensing ion channel 4.
      
 0.495
ANKRD13B
Ankyrin repeat domain-containing protein 13B isoform X1.
      
 0.490
TMEM208
Transmembrane protein 208 isoform X1.
      
 0.477
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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