Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EML3Echinoderm microtubule-associated protein-like 3 isoform X1. (896 aa)    
Predicted Functional Partners:
NEK9
NIMA (never in mitosis gene a)-related kinase 9.
   
 0.814
LAS1L
Ribosomal biogenesis protein LAS1L isoform X1.
   
 0.598
IFT140
Intraflagellar transport protein 140 homolog.
   
 0.566
GAS2L3
GAS2-like protein 3.
     
 0.549
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.544
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.
     
  0.530
NEK6
NIMA (never in mitosis gene a)-related kinase 6.
    
 0.529
RASAL3
RAS protein activator like-3.
   
 
 0.512
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.510
NEK7
NIMA (never in mitosis gene a)-related kinase 7.
    
 0.505
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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