Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MSR1Macrophage scavenger receptor types I and II isoform X1. (454 aa)    
Predicted Functional Partners:
CALML6
Calmodulin-like protein 6 isoform X1.
    
 
 0.683
F2RL3
F2R like thrombin or trypsin receptor 3.
     
 0.597
LCK
LCK proto-oncogene, Src family tyrosine kinase.
   
 0.560
ARHGAP44
Rho GTPase-activating protein 44.
      
 0.557
GUK1
Guanylate kinase 1.
    
 0.554
ALCAM
Activated leukocyte cell adhesion molecule.
    
 0.543
SPTLC1
Serine palmitoyltransferase 1.
      
 0.542
DAXX
Death domain-associated protein 6 isoform X1.
   
 0.529
APOB
Apolipoprotein B-100 isoform X1.
    
 0.528
TAPBP
TAP binding protein (tapasin).
    
 0.523
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (20%) [HD]