Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MARK4MAP/microtubule affinity-regulating kinase 4 isoform X1. (752 aa)    
Predicted Functional Partners:
YWHAB
14-3-3 protein beta/theta/zeta.
    
 0.806
KSR1
Kinase suppressor of ras 1.
   
 0.726
YWHAE
14-3-3 protein epsilon isoform X1.
    
 0.699
YWHAQ
14-3-3 protein theta isoform X1.
    
 0.687
MTCL1
Microtubule crosslinking factor 1.
    
 
 0.644
ENSPPRP00000004233
annotation not available
    
 0.583
ENSPPRP00000004694
annotation not available
    
 0.583
YWHAZ
14-3-3 protein beta/theta/zeta.
    
 0.583
KSR2
Kinase suppressor of Ras 2.
   
 0.583
YWHAH
14-3-3 protein gamma/eta.
    
 0.571
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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