Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORT1Sortilin isoform X1. (833 aa)    
Predicted Functional Partners:
NGFR
Tumor necrosis factor receptor superfamily member 16.
    
 0.990
NTS
Neurotensin/neuromedin N.
   
 
 0.964
GRN
Granulins isoform X1.
    
 
 0.933
LRPAP1
Alpha-2-macroglobulin receptor-associated protein.
    
 
 0.930
APOB
Apolipoprotein B-100 isoform X1.
     
 0.921
GGA1
ADP-ribosylation factor-binding protein GGA1 isoform X1.
    
 
 0.919
SORCS1
VPS10 domain-containing receptor SorCS1 isoform X1.
    
 0.916
GGA2
ADP-ribosylation factor-binding protein GGA2.
    
 
 0.904
BDNF
LOW QUALITY PROTEIN: brain-derived neurotrophic factor.
    
 
 0.899
SORCS2
Sortilin related VPS10 domain containing receptor 2.
    
 0.888
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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