STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB7Integrin beta 7. (797 aa)    
Predicted Functional Partners:
ITGA4
Integrin alpha-4 isoform X1.
   
 0.999
PXN
Paxillin isoform X1.
   
 0.974
ITGAE
LOW QUALITY PROTEIN: integrin alpha-E.
   
 0.973
SRC
Proto-oncogene tyrosine-protein kinase Src isoform X1.
   
 0.971
FN1
Fibronectin isoform X1.
   
 
 0.947
VCAM1
Vascular cell adhesion protein 1 isoform X1.
   
 0.946
TLN2
Talin-2.
   
 0.918
CAV1
Caveolin-1 isoform X1.
     
 0.918
TLN1
Talin-1 isoform X1.
   
 0.918
ACTG1
Actin, cytoplasmic 2.
    
 0.917
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.