Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGB7Integrin beta 7. (797 aa)    
Predicted Functional Partners:
ITGA4
Integrin alpha-4 isoform X1.
   
 0.997
ITGAE
LOW QUALITY PROTEIN: integrin alpha-E.
   
 0.996
FLNA
Filamin-A.
    
 0.980
ITGAV
Integrin alpha V.
   
 0.972
ITGA5
Integrin subunit alpha 5.
   
 0.968
ENSPPRP00000022837
annotation not available
    
 0.968
FLNB
Filamin-B.
    
 0.966
ITGA1
Integrin alpha-1 isoform X1.
   
 0.966
ITGA2
Integrin alpha 2.
   
 0.954
PTK2
Protein tyrosine kinase 2.
   
 0.944
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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