Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3. (925 aa)    
Predicted Functional Partners:
PDE10A
CAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1.
    
 0.945
PDE1B
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1.
     
 0.943
GUCY2C
Heat-stable enterotoxin receptor isoform X1.
     
 0.942
PDE7A
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1.
    
 0.938
NT5E
5'-nucleotidase isoform X1.
   
 
 0.935
PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha isoform X1.
    
 0.933
AMPD2
AMP deaminase 2 isoform X1.
   
 
 0.933
PDE6B
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta isoform X1.
    
 0.933
NT5C1A
Cytosolic 5'-nucleotidase 1A.
     
 0.932
ADK
Adenosine kinase isoform X1.
   
 
 0.932
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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