Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL13RA1Interleukin-13 receptor subunit alpha-1 isoform X1. (427 aa)    
Predicted Functional Partners:
IL13
Interleukin 13.
  
 
 0.997
IL4
Interleukin 4.
    
 0.988
TYK2
Non-receptor tyrosine-protein kinase TYK2 isoform X1.
    
 0.960
IL4R
Interleukin-4 receptor subunit alpha isoform X1.
    
 0.959
JAK1
Tyrosine-protein kinase JAK1.
    
 0.957
JAK2
Tyrosine-protein kinase JAK2 isoform X1.
    
 0.926
STAT6
Signal transducer and activator of transcription 6 isoform X1.
     
 0.923
IL15
Interleukin 15.
  
  
 0.920
LIF
Leukemia inhibitory factor.
  
  
  0.911
IL6
Interleukin-6 isoform X1.
     
 0.908
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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