Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
USP18Ubl carboxyl-terminal hydrolase 18 isoform X1. (372 aa)    
Predicted Functional Partners:
IFNAR2
Interferon alpha/beta receptor 2 isoform X1.
    
 0.989
ISG15
Ubiquitin cross-reactive protein.
   
 0.981
MX1
Interferon-induced GTP-binding protein Mx1-like.
   
 0.936
RSAD2
Radical S-adenosyl methionine domain-containing protein 2 isoform X1.
   
  
 0.925
STAT2
Signal transducer and activator of transcription 2 isoform X1.
   
 0.921
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
   
 
 0.919
IFI44
Interferon-induced protein 44.
   
 
 0.896
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
    
 
 0.893
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.890
MAP3K7
Mitogen-activated protein kinase kinase kinase 7 isoform X1.
    
 0.888
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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