STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHRS11Dehydrogenase/reductase 11. (285 aa)    
Predicted Functional Partners:
HSD17B2
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+).
  
 
 0.976
HSD17B1
Hydroxysteroid 17-beta dehydrogenase 1.
  
  
 0.975
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
     
 0.955
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase.
   
 0.952
HSD11B1
Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1.
  
  
 0.925
LOC109258417
Cytochrome P450 11B1, mitochondrial.
   
 
 0.920
HSD17B12
Hydroxysteroid 17-beta dehydrogenase 12.
   
 0.904
HSD17B8
Estradiol 17-beta-dehydrogenase 8.
     
 0.900
HSD11B1L
Hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1.
   
 0.899
CYP11A1
Cholesterol side-chain cleavage enzyme, mitochondrial isoform X1.
   
 
 0.860
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.