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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COLQAcetylcholinesterase collagenic tail peptide isoform X1. (456 aa)    
Predicted Functional Partners:
ALG14
UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform X1.
      
 0.742
MYO9A
Unconventional myosin-IXa isoform X1.
    
 0.653
SYT15
Synaptotagmin-15 isoform X1.
      
 0.623
SLC5A7
Solute carrier family 5 (high affinity choline transporter), member 7.
      
 0.619
GMPPB
Mannose-1-phosphate guanyltransferase beta.
   
  
 0.613
MUSK
Muscle, skeletal receptor tyrosine-protein kinase.
    
 0.611
PREPL
Prolyl endopeptidase-like isoform X1.
      
 0.600
ACHE
Acetylcholinesterase isoform X1.
    
 
 0.594
CHRNE
Cholinergic receptor nicotinic epsilon subunit.
    
 
 0.591
CAPN7
Calpain-7 isoform X1.
    
 0.548
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.