Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NPAS1Neuronal PAS domain-containing protein 1/3. (567 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator isoform X1.
   
 0.758
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
   
 0.758
UBXN7
UBX domain-containing protein 7.
    
  0.730
VHL
Von Hippel-Lindau disease tumor suppressor isoform X1.
    
 0.729
CUL2
Cullin 2.
    
 0.627
EGLN3
Hypoxia-inducible factor prolyl hydroxylase.
    
 0.606
EGLN1
Egl-9 family hypoxia inducible factor 1.
    
 0.606
EGLN2
Hypoxia-inducible factor prolyl hydroxylase.
    
 0.606
ELOB
Transcription elongation factor B polypeptide 2.
    
 0.559
ENSPPRP00000023592
annotation not available
    
 0.559
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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