Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIB1Tribbles homolog 1/2. (372 aa)    
Predicted Functional Partners:
COP1
E3 ubiquitin-protein ligase RFWD2 isoform X1.
    
 
 0.941
STK40
Serine/threonine-protein kinase 40 isoform X1.
    
 
 0.925
FOSL2
Fos-related antigen 2 isoform X1.
   
 0.853
TRIB2
Tribbles homolog 2 isoform X1.
    
   0.811
DET1
DET1 homolog isoform X1.
    
 
 0.808
APPL1
DCC-interacting protein 13-alpha isoform X1.
    
 0.799
APPL2
DCC-interacting protein 13-beta isoform X1.
    
 0.796
RIBC2
RIB43A-like with coiled-coils protein 2 isoform X1.
   
 0.738
CEBPE
CCAAT/enhancer-binding protein epsilon isoform X1.
   
 0.727
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha.
   
 0.727
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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