Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PGRMC1Membrane-associated progesterone receptor component 1. (195 aa)    
Predicted Functional Partners:
TMEM97
Transmembrane protein 97.
    
 0.906
PGRMC2
Membrane-associated progesterone receptor component 2 isoform X1.
   
 0.864
BCAP31
B-cell receptor-associated protein 31.
   
 0.844
CYP51A1
Lanosterol 14-alpha demethylase isoform X1.
    
 
 0.836
FECH
Protoporphyrin/coproporphyrin ferrochelatase.
    
 
 0.835
SERBP1
Plasminogen activator inhibitor 1 RNA-binding protein isoform X1.
   
  
 0.742
CYP1A1
Cytochrome P450 family 1 subfamily A polypeptide 1.
    
 
 0.719
CYP1A2
Cytochrome P450 family 1 subfamily A polypeptide 2.
    
 
 0.719
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1.
   
 
 0.716
BCAP29
B-cell receptor-associated protein 29.
   
 0.687
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.