Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NUMA1Nuclear mitotic apparatus protein 1 isoform X1. (2116 aa)    
Predicted Functional Partners:
RPUSD2
RNA pseudouridylate synthase domain-containing protein 2.
    
 
 0.547
HEATR1
U3 small nucleolar RNA-associated protein 10.
    
 
 0.538
ESF1
ESF1 homolog.
   
 
 0.505
MPHOSPH10
U3 small nucleolar ribonucleoprotein protein MPP10 isoform X1.
   
  
 0.497
UTP20
Small subunit processome component 20 homolog isoform X1.
      
 0.495
MDN1
Midasin isoform X1.
   
 0.459
SAPCD2
Suppressor APC domain-containing protein 2 isoform X1.
    
 
 0.436
NOP58
Nucleolar protein 58 isoform X1.
    
 
 0.431
BCCIP
BRCA2 and CDKN1A-interacting protein isoform X1.
   
 
 0.430
NOL11
Nucleolar protein 11 isoform X1.
    
 0.429
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.