STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFN2Profilin-2 isoform X1. (187 aa)    
Predicted Functional Partners:
ACTG1
Actin, cytoplasmic 2.
   
 0.958
DIAPH1
Protein diaphanous homolog 1 isoform X1.
    
 0.937
PFN1
Profilin-1.
     
0.936
DIAPH2
Protein diaphanous homolog 2 isoform X1.
    
 0.928
APBB1IP
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein.
    
 0.920
VASP
Vasodilator stimulated phosphoprotein.
   
 0.909
XPO6
Exportin-6 isoform X1.
    
 
 0.732
CFL2
Cofilin-2.
   
 0.707
LOC109272550
Cofilin-2-like isoform X1.
   
 0.707
WAS
WASP actin nucleation promoting factor.
   
 
 0.660
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.