STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFEBTranscription factor EB isoform X1. (549 aa)    
Predicted Functional Partners:
YWHAB
14-3-3 protein beta/theta/zeta.
    
 0.985
MTOR
Serine/threonine-protein kinase mTOR.
    
 
 0.931
MITF
Microphthalmia-associated transcription factor isoform X1.
    
0.923
TFE3
Transcription factor E3 isoform X1.
    
0.922
LAMP1
Lysosome-associated membrane glycoprotein 1.
      
 0.835
RRAGC
Ras-related GTP-binding protein C/D.
    
 
 0.803
MCOLN1
Mucolipin-1 isoform X1.
      
 0.797
CTSD
LOW QUALITY PROTEIN: cathepsin D.
     
 0.796
ENSPPRP00000023257
annotation not available
    
 
 0.657
RPTOR
Regulatory-associated protein of mTOR isoform X1.
    
 
 0.657
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.