STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UPF1Regulator of nonsense transcripts 1 isoform X1. (1130 aa)    
Predicted Functional Partners:
UPF2
Regulator of nonsense transcripts 2.
   
 0.999
SMG1
Serine/threonine-protein kinase SMG1 isoform X1.
   
 0.998
UPF3A
Regulator of nonsense transcripts 3A.
    
 0.997
UPF3B
Regulator of nonsense transcripts 3B isoform X1.
    
 0.992
SMG7
Protein SMG7 isoform X1.
   
 0.991
RBM8A
RNA-binding protein 8A isoform X1.
    
 0.986
SMG5
SMG5 nonsense mediated mRNA decay factor.
   
 0.986
SMG6
Telomerase-binding protein EST1A-like isoform X1.
   
 0.984
CASC3
Protein CASC3 isoform X1.
    
 0.977
RNPS1
RNA-binding protein with serine-rich domain 1 isoform X1.
    
 0.977
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.