Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCM9DNA helicase MCM9 isoform X1. (1143 aa)    
Predicted Functional Partners:
MCM3
DNA replication licensing factor MCM3.
   
0.988
MCM5
DNA replication licensing factor MCM5.
   
0.988
MCM7
DNA replication licensing factor MCM7 isoform X1.
   
0.987
MCM4
DNA replication licensing factor MCM4.
   
0.987
MCM8
Minichromosome maintenance 8 homologous recombination repair factor.
   
0.978
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.968
ORC1
Origin recognition complex subunit 1 isoform X1.
  
 0.960
POLA1
DNA polymerase alpha catalytic subunit isoform X1.
   
 0.958
PRIM2
DNA primase large subunit isoform X1.
   
 0.949
MCM6
DNA replication licensing factor MCM6.
   
0.936
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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