close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCM9DNA helicase MCM9 isoform X1. (1143 aa)    
Predicted Functional Partners:
MCM3
DNA replication licensing factor MCM3.
   
0.988
MCM5
DNA replication licensing factor MCM5.
   
0.988
MCM4
DNA replication licensing factor MCM4.
   
0.988
MCM7
DNA replication licensing factor MCM7 isoform X1.
   
0.986
CDT1
Chromatin licensing and DNA replication factor 1.
   
 0.985
ORC1
Origin recognition complex subunit 1 isoform X1.
  
 0.977
CDC6
Cell division control protein 6 homolog.
   
 0.977
CDC45
Cell division cycle 45.
   
 0.972
MCM10
Minichromosome maintenance protein 10.
   
 0.968
ORC2
Origin recognition complex subunit 2 isoform X1.
   
 0.966
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.