STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFWD3E3 ubiquitin-protein ligase RFWD3. (755 aa)    
Predicted Functional Partners:
RPA3
Replication protein A 14 kDa subunit.
    
 
 0.961
RPA1
Replication protein A 70 kDa DNA-binding subunit.
   
 
 0.938
PRIMPOL
DNA-directed primase/polymerase protein isoform X1.
    
 
 0.925
SMARCAL1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1.
    
 
 0.777
HMCES
Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein.
      
 0.734
TIPIN
TIMELESS-interacting protein.
   
  
 0.727
MCM8
Minichromosome maintenance 8 homologous recombination repair factor.
   
  
 0.720
WDR59
WD repeat-containing protein 59 isoform X1.
      
 0.719
MEIOB
Meiosis-specific with OB domain-containing protein isoform X1.
   
 
 0.716
GLG1
Golgi apparatus protein 1 isoform X1.
    
 
 0.637
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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