Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXP2Forkhead box P2. (712 aa)    
Predicted Functional Partners:
FOXP4
Forkhead box protein P4 isoform X1.
    
 
 0.803
FOXP3
Forkhead box P3.
    
 
 0.795
FOXP1
Forkhead box protein P1 isoform X1.
    
 
 0.723
NFATC2
Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1.
    
 0.698
RUNX3
Runt-related transcription factor 3.
    
 0.673
RUNX1
Runt-related transcription factor 1 isoform X1.
    
 0.576
RUNX2
Runt-related transcription factor 2 isoform X1.
    
 0.576
TAF1
Transcription initiation factor TFIID subunit 1 isoform X1.
    
 
 0.547
ZNF236
Zinc finger protein 236 isoform X1.
    
 0.546
MAMLD1
Mastermind-like domain-containing protein 1 isoform X1.
    
 
 0.546
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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