STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP2NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1. (870 aa)    
Predicted Functional Partners:
ARRDC1
Arrestin domain-containing protein 1 isoform X1.
    
 
 0.869
UBC
Polyubiquitin-C.
    
 0.842
NDFIP2
NEDD4 family-interacting protein 2.
    
 
 0.815
NDFIP1
NEDD4 family-interacting protein 1.
    
 
 0.800
PTEN
Phosphatase and tensin homolog.
   
 0.797
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.735
ARRDC5
Arrestin domain-containing protein 5.
    
 
 0.720
SMAD7
Mothers against decapentaplegic homolog 7 isoform X1.
    
 0.668
LOC109266006
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like.
   
 0.667
NOTCH3
Neurogenic locus notch homolog protein 3.
    
 0.663
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.