STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BARD1BRCA1-associated RING domain protein 1 isoform X1. (773 aa)    
Predicted Functional Partners:
BRCA1
BRCA1 DNA repair associated.
   
0.999
RBBP8
DNA endonuclease RBBP8 isoform X1.
    
 0.994
ABRAXAS1
BRCA1-A complex subunit Abraxas isoform X1.
    
 0.986
MRE11
Double-strand break repair protein MRE11A isoform X1.
   
 0.983
TOPBP1
DNA topoisomerase 2-binding protein 1 isoform X1.
   
 0.979
NBN
Nibrin isoform X1.
    
 0.976
BRCA2
Breast cancer type 2 susceptibility protein isoform X1.
   
 0.970
SLF1
SMC5-SMC6 complex localization factor protein 1 isoform X1.
   
0.969
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.962
BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1.
    
 0.960
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.