STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYNTyrosine-protein kinase Lyn isoform X1. (512 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase SYK isoform X1.
  
0.987
CD19
B-lymphocyte antigen CD19 isoform X1.
   
 0.987
GP6
Platelet glycoprotein VI isoform X1.
   
 0.983
FYN
Tyrosine-protein kinase Fyn isoform X1.
  
0.982
BTK
Bruton agammaglobulinemia tyrosine kinase.
  
0.973
BLNK
B-cell linker protein.
   
 0.970
PTK2B
Protein-tyrosine kinase 2-beta isoform X1.
   
0.969
CD79A
B-cell antigen receptor complex-associated protein alpha chain.
   
 0.966
SHC1
SHC-transforming protein 1 isoform X1.
   
 0.965
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.963
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.