STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA2Protein disulfide-isomerase A2 isoform X1. (526 aa)    
Predicted Functional Partners:
HSPA5
Endoplasmic reticulum chaperone BiP.
   
 0.888
HSP90B1
Heat shock protein 90kDa beta.
   
 0.823
P4HA2
Prolyl 4-hydroxylase subunit alpha-2 isoform X1.
   
 0.814
MTTP
Microsomal triglyceride transfer protein large subunit isoform X1.
   
 0.802
ERO1B
ERO1-like protein beta isoform X1.
   
 0.799
CALR
Calreticulin.
   
 0.761
CALR3
Calreticulin 3.
   
 0.761
ERO1A
ERO1-like protein alpha.
   
 0.761
ANKRD45
Ankyrin repeat domain 45.
   
 0.761
P4HA3
Prolyl 4-hydroxylase subunit alpha-3 isoform X1.
   
 0.757
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.