STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE5ACGMP-specific 3',5'-cyclic phosphodiesterase isoform X1. (865 aa)    
Predicted Functional Partners:
APRT
Adenine phosphoribosyltransferase.
     
 0.917
ITPA
Inosine triphosphate pyrophosphatase isoform X1.
     
 0.910
GMPS
GMP synthase [glutamine-hydrolyzing] isoform X1.
     
 0.902
CANT1
Soluble calcium-activated nucleotidase 1.
     
 0.901
HPRT1
Hypoxanthine-guanine phosphoribosyltransferase isoform X1.
     
  0.900
GUCY1B1
Guanylate cyclase soluble subunit beta-1 isoform X1.
   
 0.863
NPR2
Atrial natriuretic peptide receptor 2 isoform X1.
   
 0.858
PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
   
 0.857
GUCY2C
Heat-stable enterotoxin receptor isoform X1.
   
 0.835
ENTPD6
Ectonucleoside triphosphate diphosphohydrolase 6 isoform X1.
   
 
 0.829
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.