STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPPRP000000089445-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase. (472 aa)    
Predicted Functional Partners:
HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7 isoform X1.
   
 0.962
CYP27A1
Sterol 26-hydroxylase, mitochondrial-like isoform X1.
     
0.949
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase isoform X1.
   
 
 0.927
LSS
Lanosterol synthase isoform X1.
   
 0.783
FAXDC2
Fatty acid hydroxylase domain-containing protein 2.
   
 0.768
MSMO1
Methylsterol monooxygenase 1.
   
 0.768
FDFT1
Farnesyl-diphosphate farnesyltransferase.
  
 
 0.676
SQLE
Squalene monooxygenase.
   
 0.672
ERG28
Probable ergosterol biosynthetic protein 28 isoform X1.
   
 
 0.661
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
   
 
 0.657
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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