KDR protein (Panthera pardus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

KDR

Vascular endothelial growth factor receptor 2. (1356 aa)

Predicted Functional Partners:

VEGFC

0.976

VEGFA

0.974

SRC

0.970

PIK3R1

0.968

PIK3CA

0.967

PIK3R2

0.966

PXN

0.960

PIK3CB

0.959

SHC2

0.958

PLCG2

0.957

Your Current Organism:

Panthera pardus

NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KDR	PIK3CA	ENSPPRP00000011630	ENSPPRP00000009119	Vascular endothelial growth factor receptor 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.967
KDR	PIK3CB	ENSPPRP00000011630	ENSPPRP00000005645	Vascular endothelial growth factor receptor 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.959
KDR	PIK3R1	ENSPPRP00000011630	ENSPPRP00000001938	Vascular endothelial growth factor receptor 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.968
KDR	PIK3R2	ENSPPRP00000011630	ENSPPRP00000013717	Vascular endothelial growth factor receptor 2.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.966
KDR	PLCG2	ENSPPRP00000011630	ENSPPRP00000020138	Vascular endothelial growth factor receptor 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.	0.957
KDR	PXN	ENSPPRP00000011630	ENSPPRP00000003254	Vascular endothelial growth factor receptor 2.	Paxillin isoform X1.	0.960
KDR	SHC2	ENSPPRP00000011630	ENSPPRP00000021504	Vascular endothelial growth factor receptor 2.	SHC-transforming protein 2 isoform X1.	0.958
KDR	SRC	ENSPPRP00000011630	ENSPPRP00000010403	Vascular endothelial growth factor receptor 2.	Proto-oncogene tyrosine-protein kinase Src isoform X1.	0.970
KDR	VEGFA	ENSPPRP00000011630	ENSPPRP00000010070	Vascular endothelial growth factor receptor 2.	Vascular endothelial growth factor A.	0.974
KDR	VEGFC	ENSPPRP00000011630	ENSPPRP00000009489	Vascular endothelial growth factor receptor 2.	Vascular endothelial growth factor C/D.	0.976
PIK3CA	KDR	ENSPPRP00000009119	ENSPPRP00000011630	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Vascular endothelial growth factor receptor 2.	0.967
PIK3CA	PIK3CB	ENSPPRP00000009119	ENSPPRP00000005645	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.961
PIK3CA	PIK3R1	ENSPPRP00000009119	ENSPPRP00000001938	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.999
PIK3CA	PIK3R2	ENSPPRP00000009119	ENSPPRP00000013717	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.998
PIK3CA	PLCG2	ENSPPRP00000009119	ENSPPRP00000020138	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.	0.948
PIK3CA	SRC	ENSPPRP00000009119	ENSPPRP00000010403	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Proto-oncogene tyrosine-protein kinase Src isoform X1.	0.976
PIK3CB	KDR	ENSPPRP00000005645	ENSPPRP00000011630	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Vascular endothelial growth factor receptor 2.	0.959
PIK3CB	PIK3CA	ENSPPRP00000005645	ENSPPRP00000009119	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.961
PIK3CB	PIK3R1	ENSPPRP00000005645	ENSPPRP00000001938	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.999
PIK3CB	PIK3R2	ENSPPRP00000005645	ENSPPRP00000013717	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.999