STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCH1GTP cyclohydrolase 1 isoform X1. (249 aa)    
Predicted Functional Partners:
GCHFR
GTP cyclohydrolase 1 feedback regulatory protein.
    
 0.982
PTS
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase.
  
 
 0.976
ITPA
Inosine triphosphate pyrophosphatase isoform X1.
  
 
 0.940
VTA1
Vacuolar protein sorting-associated protein VTA1 homolog.
   
   0.930
MOCS1
GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase.
    
 0.921
ALPI
Intestinal-type alkaline phosphatase.
   
 
  0.901
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme.
   
 
  0.901
NUDT2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
  
 
 0.883
NUDT15
Nudix hydrolase 15.
  
 
 0.873
GUCY1A1
Guanylate cyclase soluble subunit alpha-3.
     
 0.833
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.