STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAML1Mastermind like transcriptional coactivator 1. (1016 aa)    
Predicted Functional Partners:
RBPJ
Recombining binding protein suppressor of hairless isoform X1.
   
 0.995
RBPJL
Recombining binding protein suppressor of hairless-like protein isoform X1.
   
 0.932
EP300
Histone acetyltransferase p300.
   
 0.821
JAG1
Protein jagged-1.
    
 0.732
CREBBP
LOW QUALITY PROTEIN: CREB-binding protein.
   
 0.732
NOTCH3
Neurogenic locus notch homolog protein 3.
   
 0.731
ENSPPRP00000001204
annotation not available
   
 0.707
CRB2
Protein crumbs homolog 2 isoform X1.
   
 0.707
NOTCH2
Neurogenic locus notch homolog protein 2 isoform X1.
   
 0.697
NOTCH4
Neurogenic locus notch homolog protein 4 isoform X1.
    
 0.672
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.