STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KA3Ribosomal protein S6 kinase alpha-3 isoform X1. (740 aa)    
Predicted Functional Partners:
MAPK3
Mitogen-activated protein kinase 1/3.
   
0.976
MAPK1
Mitogen-activated protein kinase 1/3.
   
0.976
MAPK7
Mitogen-activated protein kinase 7.
   
0.969
TSC2
Tuberous sclerosis 2.
    
 0.941
KRAS
GTPase KRas isoform X1.
   
 0.917
TSC1
Tuberous sclerosis 1.
    
 0.916
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
     
 0.913
NRAS
GTPase NRas.
   
 0.913
HRAS
GTPase HRas.
   
 0.913
TBC1D7
TBC1 domain family member 7 isoform X1.
     
 0.909
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.