STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRSepiapterin reductase. (267 aa)    
Predicted Functional Partners:
PAH
Phenylalanine-4-hydroxylase.
   
 
 0.994
PTS
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase.
   
 
 0.965
QDPR
Dihydropteridine reductase.
   
 0.953
TH
Tyrosine 3-monooxygenase.
   
 
 0.939
TPH1
Tryptophan 5-hydroxylase 1 isoform X1.
   
 
 0.934
TPH2
Tryptophan 5-hydroxylase 2.
   
 
 0.934
AKR1B1
Aldehyde reductase.
   
 
 0.919
LOC109249762
Carbonyl reductase [NADPH] 1-like.
     
 0.910
LOC109249756
Carbonyl reductase [NADPH] 1-like.
     
 0.910
LOC109249758
Carbonyl reductase [NADPH] 1-like isoform X1.
     
 0.910
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.