STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOXThymocyte selection-associated high mobility group box protein TOX isoform X1. (523 aa)    
Predicted Functional Partners:
GTF2H1
Transcription initiation factor TFIIH subunit 1.
    
 0.541
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
   
 0.537
SLITRK3
SLIT and NTRK-like protein 3 isoform X1.
    
 0.531
ACTR5
Actin-related protein 5.
    
 0.528
GTF2H3
General transcription factor IIH subunit 3 isoform X1.
    
 0.527
POLRMT
RNA polymerase mitochondrial.
    
 0.523
RUVBL1
RuvB-like protein 1 (pontin 52).
    
 0.521
USP18
Ubl carboxyl-terminal hydrolase 18 isoform X1.
   
  
 0.518
ST8SIA4
Alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8D).
   
  
 0.516
LOC109275038
General transcription factor IIH subunit 2 isoform X1.
   
 0.514
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.