STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SC5DDelta7-sterol 5-desaturase. (299 aa)    
Predicted Functional Partners:
DHCR7
7-dehydrocholesterol reductase.
   
 0.990
DHCR24
Delta(24)-sterol reductase.
   
 
 0.968
EBP
3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase.
   
 
 0.951
HSD17B7
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
   
 0.943
FDFT1
Farnesyl-diphosphate farnesyltransferase.
  
 
 0.927
MSMO1
Methylsterol monooxygenase 1.
  
 
0.925
FAXDC2
Fatty acid hydroxylase domain-containing protein 2.
   
 
0.920
LSS
Lanosterol synthase isoform X1.
   
 
 0.915
ERG28
Probable ergosterol biosynthetic protein 28 isoform X1.
   
 
 0.894
LBR
Delta14-sterol reductase (lamin-B receptor).
   
 0.869
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.