STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SREBF1Sterol regulatory element-binding transcription factor 1. (1174 aa)    
Predicted Functional Partners:
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
   
 0.965
PPARGC1B
Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1.
    
 0.935
SREBF2
Sterol regulatory element-binding transcription factor 2.
  
 
0.918
KPNB1
Importin subunit beta-1.
    
 0.888
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
    
 0.828
FASN
Fatty acid synthase, animal type.
   
 
 0.804
SCD
Stearoyl-CoA desaturase (Delta-9 desaturase).
   
 
 0.799
NPC1
Niemann-Pick C1 protein isoform X1.
   
 0.777
NPC1L1
Niemann-Pick C1-like protein 1 isoform X1.
   
 0.768
PPARG
Peroxisome proliferator-activated receptor gamma isoform X1.
    
 0.742
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.