STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)    
Predicted Functional Partners:
PAK1
Serine/threonine-protein kinase PAK 1.
   
 0.991
VAV1
Guanine nucleotide exchange factor VAV.
   
 0.988
VAV2
Guanine nucleotide exchange factor VAV2 isoform X1.
   
 0.985
PAK3
Serine/threonine-protein kinase PAK 3 isoform X1.
   
 0.984
PAK2
Serine/threonine-protein kinase PAK 2.
   
 0.983
NCKAP1
Nck-associated protein 1 isoform X1.
   
 0.980
IQGAP1
Ras GTPase-activating-like protein IQGAP1.
   
 0.980
PLXNB1
Plexin-B1.
   
 0.975
NCF2
Neutrophil cytosol factor 2 isoform X1.
   
 0.975
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
   
 0.974
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.