STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IZUMO1RSperm-egg fusion protein Juno. (243 aa)    
Predicted Functional Partners:
IKZF2
Zinc finger protein Helios isoform X1.
      
 0.516
MASP2
Mannan-binding lectin serine protease 2 isoform X1.
    
 0.516
PRNP
Major prion protein.
    
 0.440
ALB
Albumin.
      
 0.424
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
     
 0.421
TFRC
Transferrin receptor protein 1.
      
 0.420
SLC46A1
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1.
      
 0.418
ICOS
Inducible T-cell co-stimulator.
   
  
 0.408
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.